PPS, an FDA-approved medicine with a proven track record of managing inflammation, is being commercialized for the first time in the UK by Paradigm Pharmaceuticals. PPS was created in the 1940s and is currently widely employed to treat bladder irritation (interstitial cystitis) and prevent deep-vein thrombosis in the European Union. Taking this medication may make it easier for you to bleed. If you have unusual bleeding, contact your doctor immediately (nosebleed, blood in your urine or stools, bleeding gums, rectal bleeding, coughing up blood).
What precisely is sodium pentosan polysulfate?
Pentosan polysulfate sodium is employed to treat cystitis-related bladder pain and discomfort (bladder inflammation or irritation), approved and used by adults and children over 16 years. Because PPS has numerous modes of action, Paradigm Biopharma is focusing on investigating its usage treatment of a wide range of illnesses that originate and sustain inflammation, such as osteoarthritis (OA).
Paradigm Biopharmaceuticals (ASX: PAR) is a drug research business with a commercial focus. They established and maintained strong and effective connections with top researchers and clinicians who continue to explore relationships with several European manufacturers to bring PPS to the industry and cure unmet needs in new therapeutic areas. Furthermore, they are using a fresh approach to finding effective, safe therapies for specific therapeutic indications where patients now have few alternatives.
What to talk about with your doctor before taking PPS?
If you are hypersensitive to pentosan polysulfate sodium, you should avoid using it.
Inform your doctor if you’ve ever had:
- a blood clotting or bleeding condition;
- You or a member of the family has eye difficulties (particularly a difficulty with your retina);
- a stroke or aneurysm
- a gastric ulcer, polyps in the intestines, or diverticulitis; or
- The illness of the liver.
How does pentosan polysulfate sodium be taken?
Follow all guidelines on your pharmaceutical label and read all drug guides or instructional sheets. Use the medication precisely as instructed.
Take this medicine with a glass of water. Use on an empty stomach at least one hour before or two hours after a meal. Avoid crushing, chewing, breaking, or opening the delayed-release capsule. Your physician will need to monitor your improvement every three months to know how long treatment with pentosan polysulfate sodium is. You may also require a blood exam and eye tests to rule out potential effects.
If you require surgery, inform your surgeon that you are presently on this medication. Keep away from humidity and heat by storing at room temperature.
When you have hives, difficulty breathing, or inflammation of your face, lips, tongue, or neck in taking PPS, get medical assistance immediately.
When you are experiencing any of the following symptoms, contact your doctor right away:
- nosebleeds, gums bleeding
- blood in your stools or pee;
- bleeding in the rectum;
- spitting out blood